James Rodriguez headed home the hosts’ second before Mariano smashed in a third, but Leonesa did have a moment to savour when Yeray Gonzalez fired into the top corner from long range in first-half stoppage time.
Enzo was then handed his long-awaited bow by his father, but ensured there was to be no claims of nepotism when he finished off a flowing team move with a classy right-footed finish.
Mariano completed his hat-trick two minutes from time before a Cesar Morgado own goal.
Barcelona also fielded a side with 11 changes ahead of the Clasico, but were made to pay by third tier Hercules.
David Mainz bundled home at the back post seven minutes into the second-half to give the side form Alicante a shock lead.
However, Manchester United target Carles Alena capped his debut with a wonderful strike from 25 yards to spare Barca’s blushes.
Yannick Carrasco scored twice as Atletico Madrid also hit Guijelo for six in the first leg of their last 32 tie.
From Agencies, Feature image courtesy bestfootballers